NEW YORK (CNN) --The drugmaker Pfizer said Friday it will pay $3.4 billion in fines and other payments to settle lawsuits brought by plaintiffs who claimed their drug caused cancer and heart attacks.

"We believe there are many drug companies that can bring these types of cases," Pfizer spokesman Dan Kesselheim said. "We're not going to hold them accountable and will continue to pursue their causes."

The case was brought by the New York-based drugmaker in federal court in Brooklyn. The complaint alleges that Pfizer knew or should have known that its blockbuster arthritis drug Celebrex, marketed as the world's first-ever arthritis medication, caused heart attacks, strokes and other serious health problems.

The allegations come as Pfizer faces a $3.4 billion fine on the drug's maker, Pfizer Inc., for improperly marketing the drug.

"Pfizer has made significant investments in research, development and marketing of Celebrex. All of these investments are important to Pfizer and we are proud of our commitment to its future," said U. S. Attorney for the Eastern District of New York Rod J.okingly.

"This case is a huge victory for Pfizer," said J. P. Morgan P. Morgan in a statement. "Pfizer, through its marketing and development partnerships with other drug manufacturers, is in a position to continue to fight for the benefits of its blockbuster arthritis drug."

The suit was filed in federal court in New York. Kesselheim said Friday that the U. Food and Drug Administration has not approved Celebrex for uses in adults and children younger than 18. He also called on Pfizer to immediately stop marketing its blockbuster arthritis drug.

Celebrex is one of the world's first over-the-counter arthritis drugs. It was one of the first over-the-counter drugs approved by the FDA for use in adults and children.

Pfizer spent about $2 billion in research and development on Celebrex in 2004. The drug was approved for use in about 30 million patients in the United States. In 2004, the FDA approved Celebrex for treating arthritis. The drug's maker, Pfizer, paid the U. government $9.1 billion to settle cases for over-the-counter Celebrex. Pfizer paid $3.4 billion in payments to settle cases for its blockbuster arthritis drug.

Celebrex is the world's first over-the-counter arthritis drug, launched in 1984. It was used by more than 200,000 patients in less than three years. The FDA approved Celebrex in 1999.

The complaint alleges that Pfizer knew or should have known that its blockbuster arthritis drug, Celebrex, caused heart attacks, strokes and other serious health problems.

Pfizer paid about $3 billion in research and development on Celebrex. The drug's maker, Pfizer, paid the United States government $9.1 billion to settle cases for over-the-counter Celebrex.

Celebrex is one of the world's first over-the-counter arthritis drugs, launched in 1984. The drug was approved for treating arthritis. The company paid the United States government $9.1 billion in payments to settle cases for over-the-counter Celebrex.Celebrex is the world's first over-the-counter arthritis drug. Pfizer paid $3 billion in payments to settle cases for its blockbuster arthritis drug.

Celebrex (Celecoxib) Medication Information:

• The brand name for Celebrex is Celecoxib.
• This drug is used to treat the symptoms of inflammatory conditions like rheumatoid arthritis and ankylosing spondylitis.
• This drug does not prevent or treat viral infections.
• This drug does not prevent you from exercising.
• You cannot take a prescription for Celebrex without ever having ever had an allergic reaction to this or any other medication.
• This drug is not indicated for use in children.

General Information:

• This is not an over the counter medicine.
• This medicine may be given to you for children treatment of certain diseases.
• If you are using the medicine for the treatment of a viral infection you should see your doctor as soon as possible if you have an allergic reaction.
• If you get an allergic reaction you should not take this medicine.
• Do not take this medicine if you are allergic to any celecoxib.
• Do not give to children under 12 years old without medical advice.
• Do not take this medicine if you have had a heart attack, stroke, or heart attack in the last 6 months of your life.
• Do not take this medicine in cases of kidney failure or if you are on dialysis. If you have dialysis you may need to use this drug for longer than your doctor has prescribed.

Other information:

• This drug is also used for the treatment of:
• rheumatoid arthritis and ankylosing spondylitis
• pneumonia and acute exacerbation of chronic bronchitis
• social anxiety disorder
• symptics of an allergic reaction to Celebrex, such as

Warnings:

• Do not take Celebrex if you are allergic to celecoxib or any other ingredient in this drug
• Do not take this medicine if you have had a heart attack in the last 6 months of your life or stroke in the last 6 months of the last 10 (15) years of your life
• Take Celecoxib with a meal to avoid stomach upset
• Do not take this medicine if you are taking aspirin or other
• Do not take if you have severe kidney problems.
• Talk to your doctor or pharmacist before using Celecoxib if you are already taking another drug that may cause severe kidney problems.
• This medicine may increase the risk of developing a stroke or heart attack in certain people.
• Talk to your doctor before using Celebrex if you have had a heart attack in the last 6 months of your last 10 (15) years of life and stroke or blood clots in the legs or ankles.
• You should not take Celebrex if you are taking any other medicine.
• This medicine may make you more sensitive to the sun. To prevent this, wear protective clothing, sunscreen, and tell your doctor if you are taking any of the following drugs: warfarin (Rofecord, Branded), aspirin, warfarin (Suspension), clopidogrel (Plavix), Diclofenac, digoxin (Lanoxin), diuretics, theophylline (Adcirca, Orajel, in Erythetan), lithium (Lithobid), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), telithromycin (Kapvay), and the pill splint (Minipress). Your doctor may need to change the doses of your medicines or monitor you carefully for side effects.
• If you are taking any of the following drugs, you should talk to your doctor before using Celebrex.

Celebrex 100mg Tablet contains the active ingredient Celecoxib. It belongs to the family known as non-steroidal anti-inflammatory drugs (NSAID), and specifically a sub-group known as cyclooxygenase-2 (COX-2) inhibitors. It is used in adults for the relief of signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. In conditions like rheumatoid arthritis and osteoarthritis, excess production of prostaglandins by your body can lead to pain and inflammation. Celebrex 100mg Tablet works by decreasing the production of prostaglandins, effectively reducing pain and inflammation.

Do not take Celebrex 100mg Tablet if you are allergic to Celebrex 100mg Tablet or any of its ingredients. Inform your doctor if you had reactions to sulfonamide medicines, suffer from ulcers or bleeding in the stomach or intestines, or experienced adverse reactions to NSAID medications like aspirin.

Before starting the treatment, inform your doctor because it is recommended to not take this medicine if you are pregnant or are breastfeeding. Do not take this medicine if you have severe liver or kidney disease, have inflammatory intestinal conditions, or have heart-related issues such as heart failure, heart disease, or circulation problems. Additionally, if you have had surgeries on leg arteries or have a history of blood circulation problems, this medicine usage should be avoided. Celebrex 100mg Tablet contains lactose. If you are sugar intolerant, consult your doctor before using this product. This medicine is for adults only, it is not for use in children.

Inform your doctor about if you have a history of stomach or intestinal ulcers or bleeding (avoid if currently present), are on acetylsalicylic acid or antiplatelet therapies, use blood clotting or corticosteroid medications, or simultaneously use other non-acetylsalicylic NSAIDs like ibuprofen.

Report your doctor if you have conditions such as smoking, diabetes, high blood pressure, high cholesterol, compromised heart, liver, or kidney function, fluid retention, dehydration, past severe allergic reactions to medications, ongoing infections, or are over 65 years old. Monitoring may be necessary. Notably, Celebrex 100mg Tablet could mask fever or infection signs. Remember, alcohol combined with NSAIDs may increase gastrointestinal risks.

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Introduction About CELEBREX 200MG CAPSULE

CELEBREX 200MG CAPSULE contains Celecoxib which belongs to group of medicines called Non-steroidal anti-inflammatory drugs. CELEBREX 200MG CAPSULE is used in adults to manage osteoarthritis (degenerative joint disease), rheumatoid arthritis (inflammatory disease of joints), ankylosing spondylitis (chronic back pain), acute pain and primary dysmenorrhea (menstrual cramps).

CELEBREX 200MG CAPSULE is also used to manage juvenile rheumatoid arthritis (in children aged 2 years and above).

CELEBREX 200MG CAPSULE is not recommended for use in patients allergic to Celecoxib, sulfonamides, aspirin and/or other NSAIDs. It is also not recommended for use in patients with/had a history of an ulcer in stomach/intestines, bleeding in stomach/intestines, blood circulation problems (such as peripheral arterial disease), red itchy welts, inflammatory disease of the intestines (such as ulcerative colitis/Crohn’s disease).

The medicine is also not indicted for use in patients suffering from lung problems (such as asthma), heart diseases (such as heart failure, recent heart attack, heart block), severe liver disease (such as advanced hepatic insufficiency) and/or kidney disease (such as advanced renal insufficiency).

Before taking CELEBREX 200MG CAPSULE, inform your doctor if you have diabetes, raised blood pressure, increased cholesterol, signs of fluid retention (such as swollen ankles and feet) and/or hyperkalemia (increased potassium level in blood).

CELEBREX 200MG CAPSULE is not recommended for use in pregnant and breast-feeding women.

CELEBREX 200MG CAPSULE should be used with caution in children and adolescents (aged 2 to 17 years) to manage only juvenile rheumatoid arthritis and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.

The most common side effects of taking CELEBREX 200MG CAPSULE are high blood pressure, shortness of breath, sore throat, cough, headache, nausea and dizziness. Consult your doctor if any of these symptoms worsen.

Common side effects of taking CELEBREX 200MG CAPSULE – –

Stop taking CELEBREX 200MG CAPSULE and seek immediate medical attention if you experience the following side effects: high blood pressure, wheezing or a whistling start in the heartbeat; shortness of breath, weakness in one part or side of the body; headache; fainting. Also, get medical help if you experience symptoms of kidney problems such asuria and oliguria. Also, if you experience signs of kidney problems like kidney failure, you must consult your doctor before using CELEBREX 200MG CAPSULE. If you decide to avoid activities such asxon your days at the pool or between the sheets, you may need to take special measures to manage your kidney problems. Moreover, if you experience severe skin rash, vomiting and difficulty breathing followed by your appearance like a lota, call your doctor immediately. Also, if you experience signs of allergic reaction like rash, itching, swelling, difficulty breathing or signs of liver damage, you must consult a doctor before using CELEBREX 200MG CAPSULE.

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You have credit/new card, prescription or debit/credit card and you have ordered CELEBREX 200MG CAPSULE. Once you place an order, you will receive the product details as below: product details You will receive the product details as below: description You will receive a confirmation email containing the order quantity and the delivery address you require. Once you’ve placed an order, you will receive the product details as below: shipping and handling terms and conditions you require Shipping and handling Details We deliver the product in shampoos, polycakes, pastries, logos or packaging with fast service: We deliver it to your place of work, usually 3-5 days.

ByDr. Steven N. Ostroff, M. D., F. A. T. S.Professor of Medicine, St. Mary’s Medical Center, St. Paul, Minn., is a leading authority on the topic of “Celebrex,” a nonsteroidal anti-inflammatory drug (NSAID). This article is a summary of the ongoing work of Dr. Ostroff in his role at the Department of Medicine, St. Mary’s Medical Center.

This study is the first to evaluate the effect of a new celecoxib drug on the inflammatory response to NSAID-induced COX enzymes.

In the study, patients were divided into 2 groups: (1) patients with mild-to-moderate acute or mild-to-moderate arthritis, (2) patients with moderate-to-severe arthritis, and (3) patients with no evidence of arthritis. The patients were given celecoxib, celecoxib monotherapy, or placebo. The results of the study show that the celecoxib group had less COX-1 and COX-2 expression compared to the placebo group, although there was no difference in inflammatory response.